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r crispr high-throughput screening single-cell optical pooled screening📋 Description
- Lead design and optimization of optical pooled screening platforms
- Establish spatial multiomics workflows to study drug mechanisms
- Develop and validate high-throughput, high-content screening assays
- Design and execute screening campaigns to identify targets and validate candidates
- Integrate multi-omic datasets to drive insights and discovery strategy
- Mentor junior scientists and collaborate across disciplines on MOA
🎯 Requirements
- PhD in cell biology, molecular biology, chemical biology, pharmacology, or genomics
- 5–7+ years postdoc industry experience with leadership
- Hands-on expertise in optical pooled screening and spatial multiomics
- Strong background in high-throughput, high-content screening and CRISPR functional genomics
- Cross-functional collaboration in advancing drug discovery
- Expert cell-based assay, cell and molecular biology skills
- Proficiency in high-content imaging and automation
- Bioinformatics skills (R, Python); single-cell and multi-omic data integration
🎁 Benefits
- Stock options
- Discretionary annual bonus
- No cost health insurance plans
- 401k with company match
- Flexible paid time off
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