Quality Control (QC) Analyst II

Job Summary:

The Quality Control Analyst II is a key technical role, responsible for ensuring the accuracy, reliability, and regulatory compliance of all analytical results that support the release of raw materials, in-process samples, bulk products, stability studies, and finished goods manufactured at Crown Laboratories. This position performs a broad range of qualitative and quantitative analyses using validated methods and cGMP/GLP-compliant laboratory practices. The QC Analyst II level includes additional responsibilities such as troubleshooting, supporting method validation and verification activities, leading portions of investigations, and contributing to continuous improvement initiatives across the QC organization. The Analyst will work collaboratively with Quality Assurance, Manufacturing, and Research & Development to ensure product quality, regulatory compliance, and operational efficiency.

Reporting to: Quality Control Supervisor/Manager

Location: Johnson City, TN - onsite

Responsibilities/Essential Duties:

• Performs routine and non-routine analytical testing of raw materials, in-process samples, finished products, bulk intermediates, and stability samples in accordance with approved SOPs, compendial requirements (USP, EP), and regulatory expectations.
• Prepare reagents, standards, and sample solutions with precision, ensuring proper documentation and traceability of materials used in analytical activities.
• Operate, maintain, and troubleshoot laboratory instrumentation including but not limited to HPLC, GC, UV-Vis, FTIR, Karl Fischer, viscometers, and other analytical systems.
• Execute environmental monitoring activities (where applicable), interpret data trends, and escalate deviations per SOP.
• Accurately document all analytical data in laboratory notebooks and electronic systems (e.g. LIMS) in accordance with ALCOA+ data integrity principles and cGMP/GLP guidelines.
• Assist in laboratory investigations including OOS, OOT, and atypical results, supporting root cause analysis and corrective action implementation.
• Participate in the qualification, verification, and validation of analytical methods, equipment, and laboratory systems under the guidance of senior QC or Validation personnel.
• Support continuous improvement initiatives, including 5S, workflow optimization, and implementation of corrective/preventative actions (CAPA).
• Comply with all site-wide safety, EHS, and hazardous material handling requirements; promptly report safety concerns and near misses.
• Maintain laboratory cleanliness, readiness for internal/external audits, and adherence to cGMP expectations.
• Collaborate cross-functionally with QA, manufacturing, Supply Chain, R&D, and Validation to resolve analytical issues and support timely batch disposition.
• Perform additional duties, projects, or training assignments as delegated by QC leadership.

Basic Qualifications:

• Bachelor’s degree & 2+ years’ directly related experience; OR

Preferred Qualifications:

• Bachelor’s degree in Chemistry, or related scientific discipline.
• 2+ years’ experience in a GMP/GLP laboratory environment (industry, academic, or internship).
• Demonstrated ability to follow written procedures accurately and maintain high-quality documentation.
• Strong attention to detail, analytical thinking, and problem-solving skills.
• Effective written and verbal communication skills.
• Proficiency with Microsoft Office applications (Word, Excel, PowerPoint).
• Experience working in a regulated pharmaceutical, OTC drug, cosmetic, or medical device manufacturing environment.
• Familiarity with LIMS or other laboratory information management systems.
• Working knowledge of compendial methods (USP, EP, JP) and pharmacopeial requirements.
• Exposure to method validation/verification, analytical troubleshooting, and instrument qualification.
• Experience with data integrity, FDA 21 CFR Part 211, and ICH Q2(R2) expectations.
• Laboratory-based role requiring daily use of PPE, including lab coats, safety glasses, and gloves.
• Routine standing, walking, bending, lifting up to 25 lbs., and handling chemical reagents and laboratory materials.
• Work involves exposure to chemical substances, solvents, and analytical instrumentation in a controlled laboratory setting.

Company Summary:

Crown is a proud member of the Revance Portfolio of skincare offerings. Revance is a fast-growing global aesthetics and skincare company focused on providing innovative aesthetics and market-leading skincare offerings throughout every stage of life. With a differentiated portfolio of products spanning 60 countries, Revance meets the evolving needs of patients and consumers worldwide through continued innovation and commercialization of new products and treatments.

What Revance invests in you:

• Competitive Compensation including base salary and annual performance bonus.
• Paid time off, company holidays, and floating holidays that can be used whenever you choose.
• Generous healthcare benefits, Employer HSA match, 401k match, wellness discounts and much more.

This section of the job description is required by the American with Disability Act (ADA). The ADA requires that job descriptions reflect the physical and mental demands required to effectively perform the essential duties of the job. The ADA prohibits employers from discriminating against a “qualified individual with a disability” in all aspects of the employment relationship. A “qualified individual with a disability” is “an individual who meets the education, experience, skill, and other job-related requirements of a position held or desired, and who, with reasonable accommodation, can perform the essential functions of a specified job.”

Revance is an Equal Opportunity employer. All qualified applicants will receive consideration for employment based on merit, without regard to race, color, religion, sex, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.