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organoids liver_models target_validation oligonucleotide_therapeutics ipsc_derived_cells๐ Description
- Lead liver biology target validation (strategy, execution, interpretation).
- Lead in vitro pharmacology strategy; collaborate with in vivo pharmacology.
- Collaborate with Target Identification on in vitro models/assays for targets.
- Present data-driven go/no-go decisions on targets.
- Demonstrate leadership, accountability, and mentoring.
- Analyze and present data; publish in peer-reviewed journals when appropriate.
๐ฏ Requirements
- PhD in biological sciences; 6+ years in vitro pharmacology for genetic medicines.
- 3+ years leading teams to meet program goals.
- Hands-on experience with in vitro liver disease models and assays (steatosis, fibrosis).
- Hands-on experience with gene editing or oligonucleotide therapeutics.
- Independent, cross-functional work in fast-paced environments.
- Ability to communicate complex data to diverse stakeholders.
- Attention to detail, integrity, creativity, and collaborative mindset.
๐ Benefits
- Collaborative environment at AI-driven drug discovery frontier.
- Competitive compensation with stock ownership.
- Comprehensive health, vision, and dental coverage for employees and families.
- Flexible hours, long weekends, holiday shutdown, unlimited personal days.
- Maternity/parental leave top-up and new parent PTO.
- Learning budget and lunch-and-learns.
- Facilities in Toronto and Cambridge, MA.
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